Month: February 2020

New results on the function of the tumor suppressor HERC protein

The RAF protein could be a therapeutical target to treat the tumor growth in regulated pathways by the p38 protein, according to a new study published in the journal Scientific Reports by a team of experts of the Faculty of Medicine and Health Sciences of the UB and the Bellvitge Institute for Biomedical Research (IDIBELL). The study …

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A new model of the worm C. elegans to progress in the study of a rare disease of the nervous system

The IDIBELL Neurometabolic Diseases group, with international collaboration, has identified a model of chromosome X-linked adrenoleukodystrophy (x-ALD) in the earthworm C. elegans, this is a rare disorder of the nervous system with no treatment available.
The model will permit to accelerate and reduce the price of the research, which is studying the mechanisms and the possible pharmacological targets for the neuronal alterations of this disease.
The earliest results of studies with this organism point to glial cells as a man responsible for the neurological damage caused by the disease.

The European Commission grants IDIBELL two individual Marie Sklodowska-Curie fellowships

On February 3, the results of the 2019 call for the European program ‘Marie Sklodowska-Curie Actions – Individual Fellowships’ (MSCA IF) were published. The objective of this initiative is to promote the mobility and innovation of the intellectual capital of Europe. It has therefore a budget (this edition, €296.49 million) aimed at subsidizing the training …

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MRI could predict the effectiveness of a surgical intervention to treat one type of epilepsy

There are epilepsy patients due to sclerosis of the hippocampus who, after their removal, continue to suffer episodes of crisis. In this study, they define a method of measuring hippocampal connectivity, in the hemisphere not damaged by epilepsy, which could help predict the efficiency of surgery before the intervention, and thus better define the risks and advantages that it may entail.

Experts in G protein-coupled receptors meet at the UB to discuss new pharmacological perspectives

Within the framework of the X Esteve Foundation Discussion Group, on February 13th and 14th the tenth meeting of the working group on new advances in the field of G-protein coupled receptors (GPCR) was held at the University of Barcelona with the support of the Antoni Esteve Foundation. The meeting discussed the new knowledge regarding …

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Testing music therapy at home for patients who have suffered a stroke

A joint study between IDIBELL, Hospital del Mar, the University of Helsinki and the Spanish National Research Council funded by La Marató de TV3 tries to analyze the effects of music therapy (musical learning) once patients have finished hospital rehabilitation and are in a chronic state of the disease
To do this, they designed a keyboard linked to a smart tablet that allows the participants of the study to do their exercises at home and learn gradually in an established manner
An earlier study of the same group shows that musical therapy, like other therapies, has similar effects in motor rehabilitation for patients who have suffered a stroke, having a strong impact in mood improvement and quality of life

A clue to the pathophysiology of LCA12, a congenital form of inherited blindness

LCA12 is a form of Leber´s Congenital Amaurosis, an inherited retinal dystrophy manifested from very early ages that is characterized by severe vision loss and rapid retinal degeneration. An study on the animal model of this form of blindness reveals the GCAP proteins as mediators of the pathogenesis. Ablation of GCAPs in the mouse model substantially delays retinal degeneration. The study unveils a novel pathway of damage to consider for therapeutic purposes.

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