August 2013

High levels of RANK protein interferes with the differentiation of mammary cells

Leave a Comment / Breast cancer, Cancer, Molecular Mechanisms and Experimental Therapy in Oncology Program - Oncobell, Transformation and Metastasis / By

Researchers of the Transformation and Metastasis research group at Bellvitge Biomedical Research Institute (IDIBELL), led by Eva González-Suárez, have shown that overexpression of RANK signalling pathway interferes with the differentiation of the cells that form the mammary glands. This produces an accumulation of undifferentiated cells that finally leads to tumor development. In previous studies, the […]

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Discovered one of the mechanism that influences aggressiveness in Ewing’s Sarcoma

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Caveolin-1 participates in the formation of new blood vessels around the tumor, facilitating growth and proliferation The finding opens the door to the investigation of new therapies against this childhood cancer Angiogenesis and solid tumors Future therapies Article’s reference EphA2-induced angiogenesis in Ewing sarcoma celles works through bGFG production and is dependent on caveolin-1.

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Improvement in the diagnosis of testosterone deficiency syndrome in men allows an early treatment

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The testosterone deficiency syndrome (TDS) is a clinical and biochemical syndrome associated with advancing age. It Is produced by a gradual drop in testosterone levels which affects the sexual sphere, leading to a decrease in sexual desire and morning erections, as well as decreasing the quality and frequency of erections. It can also affect the

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IDIBELL’s researcher Eva González-Suárez awarded with a grant from Susan G. Komen® to investigate new therapies in breast cancer

Leave a Comment / Transformation and Metastasis / By

The research group leader in transformation and metastasis of the Bellvitge Biomedical Research Institute (IDIBELL), Eva González-Suárez, has been awarded with a research grant from Susan G. Komen®, the world’s leading breast cancer organization. The project is funded with 450 000 dollars for the next three years. Komen was founded in 1982 with the goal

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The epigenome differentiates the different human populations

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What makes us different? What differentiates us from our neighbors, our friends or strangers from distant countries? For years we know that there are genetic differences among different human populations that contribute to their appearance and to a different susceptibility to disease. These small genetic differences between healthy individuals are called “polymorphisms”. The group of

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