WORKSHOP “REDOX BIOLOGY IN HEALTH AND DISEASE”

Barcelona, June 27^th-28^th, 2024
Organizers: Victoria Campuzano, Gustavo Egea, Isabel Fabregat
FREE REGISTRATION! Limited number of attendees: 100.
Full program and registration available in: tgfbeta-redox.cat/workshop

Thursday 27^th
08:30 – 09:00 Registration

09:00 – 09:30  Welcome

09:30 – 11:00  SESSION 1:  ROLE OF MITOCHONDRIA IN THE REGULATION OF REDOX BIOLOGY-I. Chaired by:  Joaquim Ros, Universitat de Lleida, Lleida, Spain. 

• Antonio Enríquez, Spanish National Center for Cardiovascular Research (CNIC) and CIBERFES, Madrid, Spain. “Redox communication through mitochondria”.
• Antonio Zorzano, University of Barcelona and Institute for Research in Biomedicine and CIBEREDEM, Barcelona, Spain. “Mitochondrial fusion proteins and their role in cell homeostasis”.
• Jose-Carlos Fernández-Checa, IDIBAPS, Barcelona Clinic Hospital and CIBEREHD, Barcelona, Spain.”Mitochondrial cholesterol trafficking in metabolic-associated steatohepatitis and liver cancer”.

11:00 – 11:30  Coffee Break

11:30 – 12:30 SESSION 2:  ROLE OF MITOCHONDRIA IN THE REGULATION OF REDOX BIOLOGY-II. Chaired by:  Elena Hidalgo, Universitat Pompeu Fabra, Barcelona, Spain.

• Isabel Hernández-Álvarez, University of Barcelona, Barcelona, Spain. “Mitochondrial fusion proteins and organelle connections in metabolism“.
• Joaquim Ros, University of Lleida, Lleida, Spain “Alterations of mitochondrial function in Friedreich’s Ataxia”.

 12:30 – 13:30 OPENING KEYNOTE LECTURE.  Chaired by: Gustavo Egea, Universitat de Barcelona, Barcelona, Spain.

Victor Thannickal. Tulane University School of Medicine, New Orleans, USA). “From Oxygen to Redox Biology and Organ Regeneration”.

13:30 – 15:00  Lunch  

15:00 – 16:30  SESSION 3:  Redox Biology in Neurological (DYS)Function, and Aging. Chaired by:  Teresa Carbonell, Universitat de Barcelona, Barcelona, Spain.

• Gemma Marfany, University of Barcelona and CIBERER, Barcelona, Spain. “Bringing light to darkness: CERKL, a retinal resilience gene against oxidative stress“.
• Juan Pedro Bolaños, University of Salamanca and CIBERFES, Salamanca, Spain. “Astrocyte metabolism: energy or signaling?”.
• Juan Sastre. University of Valencia, Valencia, Spain. President of the SFRR-Europe. “Redox regulation of necroptosis in acute inflammation“.

Friday 28^th

09:30 – 11:00  SESSION 4:  redox signalling in cardiovascular pathologies. Chaired by:  Victoria Campuzano, Universitat de Barcelona, Barcelona, Spain.

 Susana Cadenas, Center of Molecular Biology Severo Ochoa – CBMSO (CSIC/UAM), Madrid, Spain. “Redox signaling and cardioprotection in ischemia-reperfusion injury”

• Vivian de Waard, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, The Netherlands: “Resveratrol as antioxidant therapy in aortic disease in Marfan syndrome”.
• María Galán, University Rey Juan Carlos (URJC), Madrid, Spain. “Targeting mitochondrial stress to limit aortic dilation in murine models of aneurysm”.

11:00 – 11:30  Coffee Break

11:30 – 12:30  SESSION 5:  NEW INSIGTHS ABOUT nadph oxidases as THERAPEUTIC TARGETS IN HUMAN DISEASES. Chaired by: Juan Sastre. University of Valencia, Valencia, Spain. President of the SFRR-Europe.

Ø  Susan M.E. Smith, Kennesaw State University, Kennesaw, Georgia, USA. “Comparison of NOX structures suggests potential new druggable site(s)”.

• Miklós Geiszt, Semmelweis University, Medical School, Budapest, Hungary. “Lessons from the rabbit model of NOX5 deficiency“.

12:30 – 13:30  CLOSING KEYNOTE LECTURE.  Chaired by:  Isabel Fabregat, IDIBELL and CIBEREHD, Barcelona, Spain.

Ulla Knaus, School of Medicine, University College Dublin, Dublin, Ireland. NADPH oxidase: culprit and protector in the intestine”.

13:30 – 14:00  CONCLUDING REMARKS.