Epidemiology of bacterial infections. Research on pathogenesis and molecular basis of antimicrobial resistance

Summary

This group’s research covers various lines of clinical and microbiological research, and includes multiple-antibiotic-resistant bacterial infectious, which are a large cause of morbidity and mortality. The study of risk factors and clinical characteristics in hospital-acquired infections, as well as the knowledge of genotypes, virulence factors and mechanisms of antibiotic resistance of bacterial pathogens, are essential for controlling epidemic outbreaks due to multi-resistant bacteria.

758 Publications

Strategic lines

Clinical and molecular epidemiology of pneumococcal disease
Clinical and molecular epidemiology of bacteraemia/sepsis
Clinical and molecular epidemiology of methicillin-resistant S. aureus infections.
Dynamic of microbial populations in exacerbations of chronic obstructive pulmonary disease.
Molecular characterisation of invasive strains of S. pyogenes.
Antimicrobial resistance: phenotype characterisation and study of molecular bases.
New techniques in microbiological diagnosis.
Application of atomic force microscopy in the study of oral biofilm.

Selected Publications

Badia Cebada,L;Peñafiel,J;Saliba,P;Andrés,M;Càmara,J;Domenech,D;Jiménez Martínez,E et al, Trends in the epidemiology of catheter-related bloodstream infections; towards a paradigm shift, Spain, 2007 to 2019., Euro Surveill, 2022;27(19):13-23, doi:10.2807/1560-7917.ES.2022.27.19.2100610

Gasch,O;Badia Cebada,L;Joao,C;Vaque,M;Pomar,V;Moreno,E;Marron,A et al, Effects of the COVID-19 Pandemic on Incidence and Epidemiology of Catheter- Related Bacteremia, Spain, Emerg. Infect. Dis, 2022;28(11):2181-2189, doi:10.3201/eid2811.220547

Sojo Dorado,J;López Hernández,I;Rosso Fernandez,C;Morales,IM;Palacios Baena,ZR;Hernández Torres,A;Merino de Lucas,E et al, Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections: A Randomized Clinical Trial., JAMA Netw. Open, 2022;5(1):doi:10.1001/jamanetworkopen.2021.37277

Favà,A;Donadeu,L;Jouve,T;Gonzalez Costello,J;Lladó,L;Santana,C; Toapanta,N et al, A comprehensive assessment of long-term SARS-CoV-2-specific adaptive immune memory in convalescent COVID-19 Solid Organ Transplant recipients., Kidney Int., 2022;101(5):1027-1038, doi:10.1016/j.kint.2021.12.029

Badia Cebada,L;Peñafiel,J;Lopez Contreras,J; Pomar,V; Martínez,JA; Santana,G; Cuquet,J et al, Decreased Mortality among Patients with Catheter-Related Bloodstream Infections at Catalan Hospitals (2010-2019)., J Hosp Infect, 2022;12670-77, doi:10.1016/j.jhin.2022.05.009

Selected Projects

FIS21052. Una perspectiva global de las enfermedades neumocócicas y la resistencia en tiempos de pandemia por COVID-19 y vacunación universal en pediatría. Instituto de Salud Carlos III (ISCIII). Budget: 217993,6. 2022-2024. PI: Ardanuy Tisaire, Carmen.

FIS21091. SEMI-AUTOMATED SURVEILLANCE OF SURGICAL SITE INFECTIONS: A STEP FORWARD TOWARD ENHANCED METHODS IN INFECTION PREVENTION AND CONTROL. Instituto de Salud Carlos III (ISCIII). Budget: 120395. 2022-2024. PI: Puig Asensio, Mireia.

CEE21030. Enhancing Whole Genome Sequencing (WGS) and Reverse Transcription Polymerase Chain Reaction (RT-PCR) national infrastructures and capacities to respond to the COVID-19 pandemic in the European Union and European Economic Area. EUROPEAN CENTRE FOR DISEASE PREVENTION AND CONTROL (ECDC). Budget: 105232,24. 2021-2022. PI: Dominguez Luzón, Mª Ángeles.

FIS22086. FI22/00279. Instituto de Salud Carlos III (ISCIII). Budget: 89900. 2023-2025. PI: Ardanuy Tisaire, Carmen.

FIS22067. CONTRATOS PARA LA INTENSIFICACION DE LA ACTIVIDAD INVESTIGADORA EN EL SNS. Instituto de Salud Carlos III (ISCIII). Budget: 60000. 2020. PI: Ardanuy Tisaire, Carmen.